Pharmacist role guide

Clinical Pharmacist: What They Do and How to Become One

Learn what clinical pharmacists do, where they work, how to become one, and how PharmD students can prepare for patient-care pharmacy roles.

By Jim Herbst, PharmD, BCPPSPublished Nov. 6, 2022Updated May 2, 20268 min read
Quick answer

What is a clinical pharmacist?

A clinical pharmacist is a licensed pharmacist who works directly with patients and healthcare teams to optimize medication therapy. Clinical pharmacists may review medication regimens, recommend therapy changes, monitor labs and outcomes, prevent medication errors, counsel patients, and support care decisions in hospitals, clinics, ambulatory care, specialty practices, and other healthcare settings.

Key facts

Use these facts as a quick orientation before reading the full guide. Exact requirements vary by school, pathway, and state.

RolePatient-care pharmacist focused on medication therapy optimization
Degree pathPharmD, pharmacist licensure, and clinical practice experience
Common settingsHospitals, health systems, clinics, ambulatory care, specialty practices, academia, and managed care
TrainingResidency is common for many clinical roles, especially in hospitals and specialty settings

Main points

Clinical pharmacy is a broad career category rather than one single job. The role usually involves applying medication expertise to patient care decisions, whether at the bedside, in a clinic, in a specialty practice, or as part of a population-health team.

Step 1

Earn a PharmD from an accredited program

Students should build a strong foundation in pharmacotherapy, calculations, medication safety, patient counseling, evidence evaluation, and interprofessional communication.

Step 2

Become licensed as a pharmacist

Graduates must complete state licensure requirements, which commonly include the NAPLEX, a pharmacy law exam such as the MPJE or a state-specific alternative, and state board documentation.

Step 3

Build clinical experience during school

Students interested in clinical pharmacy should seek APPE rotations, electives, projects, and mentors in hospitals, ambulatory care, specialty clinics, transitions of care, infectious disease, oncology, pediatrics, geriatrics, or other clinical settings.

Step 4

Consider residency training

Many clinical pharmacist roles prefer or require residency training. A PGY1 residency can support general clinical practice, while PGY2 residencies can support specialized practice areas.

Step 5

Evaluate specialty credentials when eligible

Board certification may be relevant after practice experience or residency, depending on the setting and specialty. Examples include pharmacotherapy, ambulatory care, oncology, pediatrics, psychiatry, and other specialties.

Daily work

What does a clinical pharmacist do?

Clinical pharmacists support medication decisions with a focus on safety, effectiveness, monitoring, and patient outcomes. Their responsibilities vary by setting but often include therapy review, dose adjustment recommendations, medication reconciliation, patient education, and participation in care-team discussions.

  • Review medication therapy for safety and effectiveness
  • Recommend dose adjustments or alternatives
  • Monitor labs, adverse effects, interactions, and outcomes
  • Educate patients and caregivers
  • Collaborate with physicians, nurses, advanced practice providers, and other clinicians
Work settings

Where clinical pharmacists work

Clinical pharmacists work in hospitals, ambulatory care clinics, specialty clinics, long-term care, managed care, academia, government systems, and population-health programs. The role can be generalist or highly specialized.

  • Hospital and health-system teams
  • Ambulatory care and primary care clinics
  • Specialty practices such as oncology, infectious disease, pediatrics, psychiatry, cardiology, or transplant
  • Managed care and population-health programs
  • Academic and research settings
Fit

Skills that matter in clinical pharmacy

Clinical pharmacists need strong medication knowledge, comfort with incomplete information, and the ability to communicate clearly with both clinicians and patients. The work rewards curiosity, precision, judgment, and teamwork.

  • Evidence-based pharmacotherapy
  • Patient counseling and interprofessional communication
  • Medication safety and risk assessment
  • Lab and outcomes monitoring
  • Documentation and follow-up
Comparison

Clinical pharmacist career path options

Because clinical pharmacy is broad, students should compare practice settings before choosing electives, APPEs, or residency plans.

OptionWhat it meansWhat to verify
Hospital clinical pharmacistWorks with inpatient teams and hospitalized patientsResidency expectations, rounding model, coverage schedule, and clinical service line
Ambulatory care pharmacistProvides medication management in outpatient clinicsCollaborative practice authority, clinic model, chronic disease focus, and follow-up expectations
Specialty clinical pharmacistFocuses on a defined area such as oncology, pediatrics, psychiatry, infectious disease, transplant, or cardiologySpecialty training, residency expectations, and board certification relevance
Population-health pharmacistUses data and outreach to improve medication outcomes across patient panelsQuality metrics, patient outreach model, documentation systems, and care-team structure
Checklist

How to decide if clinical pharmacy fits you

Shadow clinical pharmacists in more than one setting
Seek clinical APPE rotations
Ask about PGY1 and PGY2 expectations
Practice case-based therapeutic reasoning
Build communication and documentation skills
Learn how collaborative practice works in your state
Explore specialty board certification options
Confirm salary data is pharmacist-wide unless specialty-specific

FAQs

Is a clinical pharmacist different from a hospital pharmacist?

The terms can overlap, but they are not identical. Some clinical pharmacists work in hospitals, while others work in clinics, specialty practices, managed care, academia, or population health.

Do you need a residency to become a clinical pharmacist?

Not always, but many clinical pharmacist positions prefer or require residency training, especially in hospitals and specialty practice areas.

Can clinical pharmacists prescribe medications?

Scope varies by state, employer, and collaborative practice agreement. Some clinical pharmacists can manage or modify therapy under specific agreements, while others provide recommendations to prescribers.

Jim Herbst, PharmD, BCPPS
About the author

Jim Herbst, PharmD, BCPPS

Jim Herbst is an advanced patient care pharmacist at a nationally ranked pediatric acute care teaching hospital. He earned his Doctor of Pharmacy degree from The Ohio State University in 2012 and is board certified as a pediatric pharmacy specialist.

Opinions and information published by this author do not necessarily represent the views or opinions of his employer.

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